Sulfasalazine and Hydroxychloroquine: The Spiritual Side Effects

Please be aware I am not giving medical advice or advising anyone not to take these drugs. I am simply sharing my experience and understanding of that experience. I am not claiming there are spiritual side effects of medications as a whole.

Sometime before or around 2019, I was diagnosed with Rheumatoid Arthritis. Not necessarily because I have it, but because if I had an autoimmune issue, that was the closest match to most of my symptoms. So, I started to see a specialist for care. 

In another post, I will talk about possible reasons why my body began attacking itself and that journey. In this post, I want to share with you the spiritual side effects of two particular drugs, Sulfasalazine and Hydroxychloroquine. Before I was subscribed to these two drugs, I was on Methotrexate, a drug that is used in Chemotherapy. As a Chemotherapy drug, Methotrexate was considered a low dose of poison meant to kill off growing cells like cancer. It also would prevent people from having a successful or healthy birth as they affected all growing cells. Because I knew this, I did not really want to be on Methotrexate. I also didn’t want to be sick. I was hoping my illness would go just as quickly as it came. 

Part of me felt that the diagnosis itself was spiritual because it would manifest and disappear in the early stages. At one point, I had an X-Ray of my foot, and I had a bone spur. Then, when I went to check on how it was progressing, it disappeared. Even though I had inflammation, God had blessed that no visible effects were on my bones. However, many symptoms became worse, and my doctor upgraded me to Hydroxychloroquine. This was in 2024. It was not enough to calm my symptoms, so my doctor added Sulfasalazine. 

Now, I do not like taking medication, much-less vitamins. Around this time, I decided to be a good little patient and follow my medication regimen. At night, I begin to notice my legs move involuntarily. It would pop up every now and then as I let my body go limp before drifting off to sleep. I had no clue why until I researched and found out it could be a side effect of Hydroxychloroquine. While on Methotrexate and Hydroxychloroquine, I had tests that indicated my muscles were breaking down and being detected in my blood through Creatine levels. So,  that was when my doctor added Sulfasalazine.

Sulfasalazine was a big, round tablet. I believe I had to take one of them at night and in the day. My memory is fuzzy on the amounts, but I know I had to take pills twice a day. I am sure I could find medical visit recaps around my house if needed. As I was religiously taking all of my medication and vitamins, I began to feel electricity go through my limbs. Unpleasant ones. I am attributing it to Sulfasalazine. I complained about this to my doctor. There were signs of improvement in my overall health according to my bloodwork. 

Here is where it gets weird. Because of God’s love he shows me things spiritually in hopes I will learn and keep myself out of problems. At the time, I didn’t know it was God. I thought it was those demonic entities that kept coming around. I started to hear the pill bottle being rattled. It happened more than once. Then one day, as I was lying in my bed area something tossed the Sulfasalazine in the air. It was tossed in a way that you knew something was standing over me and wanted to get my attention. 

This is unfortunately my first post on my blog, so you are missing a lot of background information on me. I had tons of spiritual experiences, and when God allowed me to escape an abusive ex and come back to my mom’s house, the spiritual activity ramped up. At the time, I compared myself to Jonah and the prodigal son. I left to do my own thing and almost got severely hurt. God let me go back home to continue the work he told me to do in the first place. But I  was met with a host of spiritual enemies. Which I will talk about as God leads me to. 

Needless to say, a pill bottle being tossed in the air was not the most disturbing thing I have seen. So, I took a mental note but acted as if I ignored it. Unknown to me at the time. There was an entity in my room that I assumed was evil, like the rest. Now, I must tell you in the room I am currently in, it was unprecedented that things would move in it. However, I believe this entity destroyed my television, pulled down my huge Pooh Bear after trying to do deliverance on myself, and moved something around the time I was throwing out make-up. 

Now, if you know about deliverance, these items being touched will make you realize that maybe the entity was trying to help me get rid of “open doors” or the licenses I had given the enemies to operate in my room. My first reaction was that it was trying to scare me. Initially, I thought my television was broken because I started playing Psalms at night on it.  I had no clue the things I was watching were open doors. I didn’t know demons and fallen angels felt I was a threat to their agenda. My return ruined the enemies’ plans to nullify me.

To the people who do not believe in Jesus wholeheartedly, what I said may just sound like I lost some screws. The title is called the spiritual side effect for a reason. If you believe there is a God, then you know other things exist. If you believe in Jesus and read the Bible, then you know a big part of his ministry was getting rid of demons. You will also know Satan is a fallen Angel and he fell with a ⅓ of heaven. Which we do not know how much is a third of heaven. They are not just twiddling their thumbs waiting for Jesus to come back. No way, they are trying to get us to go to hell with them by setting up spiritual traps. One of those many traps is through medicine. 

I stopped taking both medications and only kept taking Methotrexate. My legs still involuntarily moved, but not as much. The unpleasant electricity I was feeling stopped. One night, I was sleeping, and I saw into the spiritual realm. This part of the realm was pitch black. I believe it was not the first time I have seen this space before. There was a demon wearing what I could best describe as a human suit. 

When I came back in 2023, God allowed me to see when demons were masquerading as humans in my dreams. Since my mid-twenties, sometimes I would see them as they really are. This demon was staring at me even though I was not physically in the void with him. I was looking into the spiritual world. His eyes were fixated on me as he only moved his arms in repetition. This demon was doing the movements of a viral dance called the floss. I woke up, and I am doing the floss. My knees were in the air just enough to lift my body off the bed to give me room to swing my arms as he did. 

After I wake up, I begin “racking my brain” to know whether I am possessed, channeling, being mind-controlled, and so on. I am sorry to say I do not have the answer to this experience. Be careful of people who seem to always have an answer for every spiritual thing. This situation may be associated with my watching social media videos more than the medication. Only God knows. However, the following accounts are definitely tied to the medications. 

In 2025, I decided to walk someone through deliverance outside of the person who was mentoring me. That was right before I found out my mentor, a Christian Counselor and  Pastor, was actually doing witchcraft. While walking the individual through a deliverance book I bought, coupled with the guidance of the Trinity (God, Jesus, and the Holy Ghost), I realized I was being delivered also. One of the things  I was delivered from was the spirit of Pharmakeia. As I was writing this, I looked up the word for the first time. I am utterly shocked by what I found. Pharmakeia is a Greek word for witchcraft and sorcery. Not only is it found twice in the bible and is the root word for terms we use today, "pharmacy" and "pharmaceutical". Insane. 

This is why we suffer from a lack of knowledge. Like lambs to the slaughter. I am so shocked right now, but not more shocked than I was about what happened after the deliverance session. The person who I helped delivered is spiritually gifted to see everything going on around her spiritually. So, she was able to see everything when I called up the spirits to leave. I know I am supposed to share this with you because Jesus made it a point to have her describe what she saw to me. Pharmakeia came out as flies; I am not sure what types of flies, but needless to say, living things do not carry flies. 

This deliverance session took from around 6:30 pm to a little after 12 midnight. I go to bed, and both my spiritual legs are being lifted in the air by someone who looks like a mad scientist. As I feel all of this in real life, I begin calling for Jesus. I hear a voice I believe is Jesus, saying, “You are supposed to cast it out.”  I believe God wanted me to live in my authority as Jesus lived in his. I can’t say for sure the spirit who looked like a scientist was the one moving my legs all the time, but I do believe it is tied to the medication. 

I do not have all the answers. All I know is I have a mandate to share all I know. I am behind schedule, and souls are at stake. Take everything you read or hear to God in prayer. He will confirm and reveal everything you need to know. I hope this helps someone in some way. Let's talk about it. Feel free to comment below.